AI and Microsoft’s cloud business are growing at a rapid pace.
AI META investments become a more in -depth users’ commitment and higher advertising revenue.
Amazon and Vertex are quickly building wealth for investors.
10 shares we like better than Microsoft ›
The US stock market was anything but calm in 2025, as several factors, including the constant trade tension, the growing macroeconomic uncertainty, and the geopolitical challenges that have weighed the common moods of investors.
But forged investors know this: market instability periods offer a chance to acquire fundamentally strong, high quality shares with stable growth prospects and strong competitive moat at attractive levels of evaluation. Historically, this strategy gave a beautiful return to patient investors.
Image source: Getty Images.
Against this background, these four shares can be exceptional photos for purchase and detention over the next decade.
Few companies are better positioned to drive the wave of artificial intelligence (AI) than Microsoft(Nasdaq: msft)S The company plays a critical role in the construction of AI infrastructure around the world. His deep partnership with Chatgpt Openai developer allowed him to infuse AI throughout his ecosystem. Copilot, his AI -powered assistant integrated into Office 365 Suite and GitHub, is ready to become a key revenue engine in the coming years.
There is then Azure, Microsoft Cloud Computing Platform, which now commands a 22% market share worldwide in AI infrastructure space. The company also builds new data centers worldwide, opening new facilities in 10 countries only in the third quarter. This laid the basis of the future growth of Azure.
His extremely diversified business model with repetitive revenue streams really distinguishes Microsoft. The company’s annuity (the ratio of its revenue, derived from repetitive sources such as subscriptions and long -term contracts), was very high 98% in the fiscal third quarter of 2025, which ended on March 31. Commercial remaining execution obligations, a barometer for measurement of future revenue, also increased by 34% in the year to $ 315. The balance is also healthy, with a cash balance of $ 79.6 billion. This allowed Microsoft to pursue an aggressive AI investment strategy while returning $ 9.7 billion to shareholders as dividends and stock buying.
All these factors make Microsoft an intelligent choice now.
Meta platforms’ (Nasdaq: Meta) The dominance in digital advertising and the solid growth prospects make it attractive to long -term investors. The company generated nearly $ 41.4 billion in revenue in the last quarter, reaching $ 3.4 billion daily in its social media applications, almost 40% of the world population.
Meta’s AI investment is already showing a tangible return. The AI AI Power Supply Recommendation System has increased the time spent on Facebook by 7% and Instagram by 6% in the last six months. The new AI Recommendation model for drums has increased the percentage of AD conversion by 5%. The Meta AI virtual assistant has nearly 1 billion monthly active users.
In addition, there are other roads to ensure the Meta large client base. The company aims to use WhatsApp’s massive user base to strengthen its business messages and the position of mobile trade in developed markets.
Meta is an extremely profitable and free cash flow company that plans to invest nearly $ 64 billion to $ 72 billion in a fiscal 2025. Given healthy queues, Meta seems worth choosing now.
Amazon (Nasdaq: AMZN) It stands for several growth catalysts over the next decade. AWS dominates the 29% cloud infrastructure services market. The Cloud Computing platform has achieved an annual revenue rate of $ 117 billion with a 40% margin at the end of the first quarter of the fiscal 2025.
The company’s e -commerce business is also enhanced thanks to the newly designed input network, increasing the acceptance of robotics and automation and expanding the same delivery sites. Finally, the ad also became a significant growth engine, generating $ 13.9 billion in revenue in the first quarter.
Amazon also uses its sophisticated AI capabilities within e -commerce, cloud calculations, advertising and all other business areas to increase productivity and improve cost efficiency. Executive Director Andy Jassi confirmed that the AI business is already a “multi -billion annual course of running” that “increases [at] Three-digit percentages during the year, “Although it is at the nascent stages. The company offers custom Trainium 2 chips, which have 30% to 40% better ratios between price and performance than competitors. In the meantime, their own NOVA and Bedrock Platform Foundation models help many large customers make custom AI applications.
With a stable major business and a fast -growing AI business, Amazon can become a significant machine for generating wealth in the coming years.
Vertex Pharmaceuticals– (Nasdaq: VRTX) The dominance of the cystic fibrosis market (CF) and its successful diversification in pain management position it as an exceptional long -term investment opportunity now.
Vertex generates over $ 10 billion annual revenue from CF. The triple combination of CF Trikafta (also known as Kaftrio outside the United States) is the main revenue engine and can cure nearly 95% of CF patients in major markets. In addition, the recently approved CF drug Alyftrek demonstrates even better therapeutic efficacy in clinical trials and is effective for 31 additional CF genetic mutations not covered by Trikafta. Plus, the medicine offers improved patient convenience with dosage once a day compared to the dosage of Trikafta twice a day. This can further expand the entry of the top of the CF.
Beyond CF, Vertex Pain Management Displays a strong early adoption and expansion of the payer’s cover. With the government’s government policy firmly in favor of alternatives to non-surgery, the company sees enormous potential for growth in this oral non-operative drug.
The Vertex pipeline includes numerous late -stage programs with three potential submission expected by 2026. The acquisition of the company from alpine immune science also added numerous potential candidates for renal disease drugs to its research piping.
Vertex is financially stable with $ 11.4 billion in cash. Therefore, the company has considerable financial flexibility to invest in initiatives for organic and inorganic plants. Given the many queues and the financial power of Vertex, the shares are an overwhelming choice now.
Before you buy Microsoft shares, think about it:
Thehe Motley Fool stock adviser Analyst team has just identified what they think is 10 best shares For investors to buy now … and Microsoft was not one of them. The 10 shares that made the abbreviation could lead to the return on monsters in the coming years.
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*Stock Advisor since May 19, 2025
John Maki, former CEO of Whole Foods Market, a subsidiary of Amazon, is a member of the Board of Directors of Motley Fool. Randy Zuckerberg, a former director of the Facebook Development Market and a sister of Meta Platforms CEO Mark Zuckerberg, is a member of the Board of Directors of Motley Fool. Malnal Pradhan has no position in any of the mentioned shares. Motley Fool has positions and recommends Amazon, Meta platforms, Microsoft and Vertex Pharmaceuticals. Motley Fool recommends the following options: Long January 2026. $ 395 Microsoft calls and short January 2026 $ 405 Microsoft calls. Motley Fool has a policy of disclosure.
4 Monster shares to buy and detention in the next decade were originally published by Motley Fool
